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Targeting DNA hypermethylation: Computational modeling of DNA demethylation treatment of acute myeloid leukemia

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In acute myeloid leukemia (AML) DNA hypermethylation of gene promoters is frequently observed and often correlates with a block of differentiation. Treatment of AML patients with DNA methyltransferase inhibitors results in global hypomethylation of genes and. thereby. can lead to a reactivation of the differentiation capability. https://cosmeticssquadets.shop/product-category/nutrition-drinks/
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